Garsorasib
Garsorasib is InventisBio's KRAS G12C-blocking pill, approved in China in 2024 for previously treated lung cancer with that mutation.
Overview
Approved by the NMPA in August 2024 for KRAS G12C-mutant advanced NSCLC after prior systemic therapy, on a single-arm phase 2 trial that followed the phase 1 study published in the Journal of Thoracic Oncology in 2023. With fulzerasib it made China the second market with domestic KRAS G12C inhibitors; combination studies with EGFR antibodies and SHP2 inhibitors are under way.
Compare all products across the US, EU, UK, Japan, China and Australia →
Approvals
| Region | Year | Indication |
|---|---|---|
| China | 2024 | KRAS G12C-mutant advanced NSCLC after at least one systemic therapy |
Trials
topRecruiting now (live from ClinicalTrials.gov)
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Latest papers
topQuery for this drug: (TITLE:"Garsorasib" OR ABSTRACT:"Garsorasib" OR TITLE:"D-1553" OR ABSTRACT:"D-1553") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Garsorasib, not a curated reading list.
Pages like this
not linked directly; found by shared links- ProductFulzerasib
Shares KRAS mutation subtypes (G12C, G12D, G12V), KRAS & RAS inhibitors, RAS / RAF / MEK / ERK (MAPK), KRAS and the tag china.
- CompanyBetta Pharmaceuticals
Shares InventisBio and the tag china.
- ProductIcotinib
Shares RAS / RAF / MEK / ERK (MAPK), Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.
- ProductFurmonertinib
Shares RAS / RAF / MEK / ERK (MAPK), Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.
- ProductSavolitinib
Shares RAS / RAF / MEK / ERK (MAPK), Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.
- ProductAumolertinib
Shares RAS / RAF / MEK / ERK (MAPK), Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.
- TrialALTER 0303
Shares Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.
- TrialAENEAS
Shares Small-molecule kinase inhibitors, Non-small-cell lung cancer and the tag china.