GIM-122 is an experimental humanised IgG1 kappa dual-functioning monoclonal antibody from Georgiamune, in phase 1 trials for advanced solid malignancies.
GIM-122 (GIM122) is a humanised IgG1 kappa dual-functioning monoclonal antibody from Georgiamune. A dual-functioning antibody that the company says overcomes cancer-mediated immune suppression and at the same time stimulates activated T cells; targets not disclosed. Its furthest stage is phase 1, for advanced solid malignancies. ClinicalTrials.gov registers it in one study linked below. FDA IND clearance August 2023; phase 1/2 recruiting per registry (NCT06028074). Whether it works in people has not been established unless a trial below reports it.
A dual-functioning antibody that the company says overcomes cancer-mediated immune suppression and at the same time stimulates activated T cells; targets not disclosed.
1.GIM-122 binds its target.
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Query for this drug: (TITLE:"GIM-122" OR ABSTRACT:"GIM-122" OR TITLE:"GIM122" OR ABSTRACT:"GIM122") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about GIM-122, not a curated reading list.
Shares Georgiamune, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Georgiamune and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Metastatic cancer (cancer that has spread) and the tag pipeline.
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