IDRX-42
IDRX-42 is an experimental small-molecule drug from GlaxoSmithKline in phase 3 trials for gastrointestinal stromal tumour, with its target not yet stated publicly.
Overview
IDRX-42 is a small-molecule drug developed by GlaxoSmithKline. Its molecular target is not stated in the ClinicalTrials.gov intervention record, and OnCo has not confirmed one from the sponsor's pipeline page. It is the investigational product in 1 recruiting or active industry-led phase 2 and phase 3 interventional cancer trial, including the phase 3 study NCT07218926 (A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumours After Imatinib Therapy), in gastrointestinal stromal tumour. The largest, NCT07218926, plans to enrol 450 participants with primary completion expected 2028-05-30. Status reflects the highest phase registered on ClinicalTrials.gov at the 2026-09-11 check; no efficacy results are recorded here.
Trials
topTrials recruiting now
Country and place are remembered in this browser only. A postcode is sent to OpenStreetMap's Nominatim service to find coordinates when you press the button; nothing else leaves your device.
Landmark trials
Latest papers
topQuery for this drug: (TITLE:"IDRX-42" OR ABSTRACT:"IDRX-42" OR TITLE:"velzatinib - subject to USAN approval" OR ABSTRACT:"velzatinib - subject to USAN approval") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about IDRX-42, not a curated reading list.
Similar pages
not linked directly; found by shared links- TreatmentVelzatinib
Shares GSK, Gastrointestinal stromal tumour (GIST) and the tags pipeline, ctgov-ingest.
- TreatmentNB003
Shares Gastrointestinal stromal tumour (GIST) and the tags pipeline, ctgov-ingest.
- TreatmentBezuclastinib
Shares Gastrointestinal stromal tumour (GIST) and the tags pipeline, ctgov-ingest.
- TreatmentCobolimab
Shares GSK and the tags pipeline, ctgov-ingest.
- TrialA Study to Investigate Velzatinib Compared With Imatinib in Adult Participants With Previously Untreated Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (StrateGIST Frontline)
Shares GSK, Gastrointestinal stromal tumour (GIST) and the tag ctgov-ingest.
- TreatmentA166
Shares the tags pipeline, ctgov-ingest.
- TreatmentAAA817
Shares the tags pipeline, ctgov-ingest.
- TreatmentABBV-706
Shares the tags pipeline, ctgov-ingest.