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INV-8989 is an experimental form not stated by the company or the registry from Shenzhen Ionova Life Sciences, in phase 1 trials for colorectal cancer, non-small cell lung cancer and pancreatic adenocarcinoma and other cancers.
INV-8989 is a form not stated by the company or the registry from Shenzhen Ionova Life Sciences. Tested in solid tumours harbouring KRAS G12D mutations; neither the registry nor the company website states the molecule's mechanism or modality. Its furthest stage is phase 1, for colorectal cancer, non-small cell lung cancer, pancreatic adenocarcinoma and ovarian cancer. ClinicalTrials.gov registers it in one study linked below. Phase 1/2 first-in-human, recruiting, started 2026-06-01 (registry). Whether it works in people has not been established unless a trial below reports it.
Tested in solid tumours harbouring KRAS G12D mutations; neither the registry nor the company website states the molecule's mechanism or modality. Connects to KRAS.
1.INV-8989 slips into a pocket on KRAS.
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Query for this drug: (TITLE:"INV-8989" OR ABSTRACT:"INV-8989") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about INV-8989, not a curated reading list.
Shares KRAS, Endometrial cancer, Ovarian cancer, Pancreatic ductal adenocarcinoma and the tag pipeline.
Shares Endometrial cancer, Ovarian cancer, Pancreatic ductal adenocarcinoma, Colorectal cancer and the tag pipeline.
Shares Endometrial cancer, Ovarian cancer, Pancreatic ductal adenocarcinoma, Colorectal cancer and the tag pipeline.
Shares Shenzhen Ionova Life Sciences, Endometrial cancer, Ovarian cancer and the tag pipeline.
Shares Shenzhen Ionova Life Sciences, Endometrial cancer, Ovarian cancer and the tag pipeline.
Shares Pancreatic ductal adenocarcinoma, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Endometrial cancer, Ovarian cancer, Colorectal cancer, Non-small-cell lung cancer and the tag pipeline.
Shares Endometrial cancer, Ovarian cancer, Non-small-cell lung cancer and the tag pipeline.
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