OnCo
ideasIdea

Remove the fallopian tubes during any pelvic surgery once childbearing is finished

Most ovarian cancers start in the fallopian tubes. Removing the tubes at hysterectomy, or instead of tying them, as British Columbia has done, appears to prevent ovarian cancer.

British Columbia's opportunistic salpingectomy programme shows reduced serous ovarian cancer incidence in early follow-up. Propose making salpingectomy the default at hysterectomy and for permanent contraception in all health systems, with registry evaluation.

Hypothesis
Programme-wide opportunistic salpingectomy reduces high-grade serous ovarian cancer incidence by at least 40% in the exposed cohort at 15 years.
Rationale
Tubal origin of high-grade serous cancer; no known effect on ovarian function; salpingectomy is also a more effective sterilisation than ligation.
What would test it
Run registry-based cohort comparisons across adopting jurisdictions.
Maturity
being tested at scale
Who has to act
clinic
Cost to try
Small (under $1M)
Years to first evidence
8
Bottlenecks it attacks

Connected

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