key papersKey paper
Non-epithelial ovarian cancer: ESMO clinical practice guidelines
The ESMO guideline on the rarer ovarian cancers, including granulosa cell and other sex cord-stromal tumours and germ cell tumours, sets out surgery, when chemotherapy is needed, fertility preservation and long-term follow-up.
Overview
Evidence-based guideline covering diagnosis, staging, surgical management including fertility-sparing surgery, adjuvant and recurrent-disease chemotherapy, hormonal therapy and follow-up for malignant germ cell tumours and sex cord-stromal tumours of the ovary.
GuidelineChanged practice
Authors
Ray-Coquard I, Morice P, Lorusso D, et al.
Published
Annals of Oncology, 2018
What it means
The observation after complete surgery for stage I granulosa cell tumour, lifelong inhibin monitoring and endocrine or bevacizumab-based options at relapse follow this guideline.
Caveats
- Evidence in sex cord-stromal tumours is largely retrospective.