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The European guideline for rectal cancer: how MRI decides the treatment, when radiotherapy is given before the operation, and how the mesorectum is removed.
ESMO Clinical Practice Guidelines for rectal cancer, published in Annals of Oncology in 2017 by Glynne-Jones, Wyrwicz, Tiret, Brown, Rödel, Cervantes and Arnold for the ESMO Guidelines Committee. Europe PMC indexes no abstract for this article, so OnCo carries no figures from it.
Its organising idea is risk stratification by MRI: the distance from the tumour or an involved node to the mesorectal fascia, extramural venous invasion and nodal status decide whether a patient has surgery alone, short-course radiotherapy, or long-course chemoradiotherapy before total mesorectal excision.
The document behind the MRI-first rectal cancer pathway used across Europe and the UK; the total neoadjuvant therapy trials (RAPIDO, PRODIGE 23, OPRA) that came after it are the main reason an update was needed.
Shares Short-course radiotherapy followed by chemotherapy before total mesorectal excision versus preoperative chemoradiotherapy in locally advanced rectal cancer (RAPIDO), Total mesorectal excision (TME), Radiotherapy, Chemoradiation (chemoradiotherapy, CRT) and the tag colorectal-evidence.
Shares Total mesorectal excision (TME), Radiotherapy, Neoadjuvant / adjuvant / perioperative, IMRT / IGRT (modern external beam) and the tag colorectal-evidence.
Shares Andrés Cervantes, ESMO Clinical Practice Guidelines & MCBS, European Society for Medical Oncology (ESMO), Annals of Oncology and the tag colorectal-evidence.
Shares Total mesorectal excision (TME), Radiotherapy, Chemoradiation (chemoradiotherapy, CRT), IMRT / IGRT (modern external beam) and the tag colorectal-evidence.
Shares ESMO Clinical Practice Guidelines & MCBS, European Society for Medical Oncology (ESMO), Annals of Oncology, Neoadjuvant / adjuvant / perioperative and the tag colorectal-evidence.
Shares Total mesorectal excision (TME), Radiotherapy, Neoadjuvant / adjuvant / perioperative, MRI and the tag colorectal-evidence.
Shares Short-course radiotherapy followed by chemotherapy before total mesorectal excision versus preoperative chemoradiotherapy in locally advanced rectal cancer (RAPIDO), Total mesorectal excision (TME), Radiotherapy, MRI and the tag colorectal-evidence.
Shares Short-course radiotherapy followed by chemotherapy before total mesorectal excision versus preoperative chemoradiotherapy in locally advanced rectal cancer (RAPIDO), Total mesorectal excision (TME), Radiotherapy, MRI and the tag colorectal-evidence.