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In ten UK centres, women having radiotherapy for left breast cancer were taught to hold a deep breath during treatment without any machine to help. Ninety-five per cent had a lower heart dose as a result, and the average heart dose fell from 1.8 to 1.1 Gy.
Bartlett and colleagues recruited 101 women in 2014 at 10 UK centres after surgery for early left breast cancer, selected because part of the heart lay inside the 50 per cent dose line on a standard free-breathing plan. Each had a second planning scan in voluntary breath-hold and was treated with the breath-hold plan. Of 93 with primary endpoint data, 88 (95 per cent) achieved a lower mean heart dose. Mean doses for free breathing and breath-hold were 1.8 and 1.1 Gy to the heart and 12.1 and 5.4 Gy to the left anterior descending coronary artery. Daily portal imaging gave population systematic errors of 1.3 to 1.9 mm and random errors of 1.4 to 1.8 mm. Median CT and treatment session times were 21 and 22 minutes.
Breath-hold for left breast radiotherapy can be delivered without special breathing equipment across ordinary NHS departments, and lowers heart dose in almost everyone selected for it.
Shares Deep inspiration breath-hold (DIBH), Respiratory motion management (4D-CT, gating, breath-hold, tracking), HER2-positive breast cancer, Triple-negative breast cancer (TNBC) and the tags precision, radiation.
Shares Surface-guided radiotherapy (SGRT) and the tags precision, radiation.
Shares the tags precision, radiation.
Shares the tags precision, radiation.
Shares the tags precision, radiation.
Shares the tags precision, radiation.
Shares the tags precision, radiation.
Shares the tags precision, radiation.
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