The 2019 WHO classification of tumours of the digestive system
The current WHO rulebook for cancers of the gut, which among other changes renamed goblet cell carcinoid as goblet cell adenocarcinoma, adopted the LAMN terminology for appendiceal tumours and re-graded neuroendocrine neoplasms.
Overview
Overview by the WHO Classification of Tumours Editorial Board of the fifth-edition digestive system volume, summarising changes across oesophagus, stomach, small bowel, appendix, colorectum, liver, biliary tract and pancreas.
For the appendix it adopts low-grade and high-grade appendiceal mucinous neoplasm and reclassifies goblet cell carcinoid as goblet cell adenocarcinoma with a three-tier grade; it also separates neuroendocrine tumours from neuroendocrine carcinomas and introduces molecular subtypes across sites.
The names on an appendix or small bowel pathology report, and hence which OnCo subtype page applies, follow this classification.
- The summary paper describes the changes; the full volume holds the diagnostic criteria.
- Some renamings (goblet cell adenocarcinoma) are still working through registries and older literature.
Similar pages
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Shares Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
- TermColectomy
Shares Goblet cell adenocarcinoma of the appendix, Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Localised small bowel adenocarcinoma (stage I to III, resected), Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
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Shares Goblet cell adenocarcinoma of the appendix, Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
- Key paperThe Chicago Consensus on peritoneal surface malignancies: management of appendiceal neoplasms
Shares Goblet cell adenocarcinoma of the appendix, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
- TermPeritoneal metastasis
Shares Goblet cell adenocarcinoma of the appendix, Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
- CancerAppendiceal cancer and pseudomyxoma peritonei
Shares Goblet cell adenocarcinoma of the appendix, Low-grade appendiceal mucinous neoplasm and pseudomyxoma peritonei, Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).
- TermEndoscopy (EGD, EUS, ERCP)
Shares Goblet cell adenocarcinoma of the appendix, Localised small bowel adenocarcinoma (stage I to III, resected).
- TermLymphadenectomy (lymph node dissection)
Shares Goblet cell adenocarcinoma of the appendix, Localised small bowel adenocarcinoma (stage I to III, resected), Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell).