Colectomy
Removing the part of the colon containing the cancer along with its blood supply and lymph nodes, then joining the ends.
Right or left hemicolectomy removes the affected half of the colon; the bowel is usually reconnected without a permanent stoma. Laparoscopic colectomy is oncologically equivalent to open surgery (COST, CLASICC). At least 12 nodes should be examined for accurate staging; adjuvant FOLFOX or CAPOX follows for stage III and high-risk stage II, increasingly guided by ctDNA (DYNAMIC, CIRCULATE). Rectal cancer uses different operations (total mesorectal excision, abdominoperineal resection).
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not linked directly; found by shared links- TermTotal neoadjuvant therapy (TNT, rectal cancer)
Shares Total mesorectal excision (TME), FOLFOX, FOLFIRI, FOLFIRINOX and CAPOX, Colorectal cancer.
- TermStoma (colostomy, ileostomy, urostomy)
- IdeaStrip the platelet coat off travelling tumour cells in ctDNA-positive patients
Shares DYNAMIC, CIRCULATE-Japan (GALAXY / VEGA / ALTAIR), Colorectal cancer.
- IdeactDNA-guided adjuvant therapy as the default in stage II-III colon cancer
Shares DYNAMIC, CIRCULATE-Japan (GALAXY / VEGA / ALTAIR), Colorectal cancer.
- IdeaA national platform trial that every ctDNA-positive patient can join
- IdeaFormally qualify tumour-DNA blood tests as a surrogate endpoint for adjuvant trials
- ProductOxaliplatin
Shares FOLFOX, FOLFIRI, FOLFIRINOX and CAPOX, Colorectal cancer.
- ProductTrifluridine/tipiracil
Shares CIRCULATE-Japan (GALAXY / VEGA / ALTAIR), Colorectal cancer.