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The paper that introduced anchored multiplex PCR, a way of finding gene fusions in tumour samples without knowing the partner gene.
Validation of a gene rearrangement panel on 319 fixed tumour samples showed 100 per cent sensitivity (95% confidence limit 96.5 to 100) and 100 per cent specificity against reference assays; the method found new fusions including ARHGEF2-NTRK1 in glioblastoma.
The basis of the FusionPlex panels many laboratories use.
Shares Archer FusionPlex panels, RNA sequencing & expression profiling.
Shares Archer FusionPlex panels, RNA sequencing & expression profiling.
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