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The laboratory validation of Foundation Medicine's tumour RNA fusion test in 189 tumour samples.
FoundationOne RNA detects fusions in 318 genes and measures expression of 1,521 genes. Against orthogonal assays, positive percent agreement was 98.28 per cent and negative percent agreement 99.89 per cent; it found a low-level BRAF fusion that orthogonal whole-transcriptome sequencing missed.
A targeted RNA test can supplement DNA profiling for fusions.
Shares Biomarker, RNA sequencing & expression profiling, Comprehensive genomic profiling.
Shares FoundationOne RNA, RNA sequencing & expression profiling.
Shares RNA sequencing & expression profiling, Comprehensive genomic profiling.
Shares FoundationOne RNA, RNA sequencing & expression profiling, Comprehensive genomic profiling.
Shares RNA sequencing & expression profiling, Comprehensive genomic profiling.
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