peoplePerson
Miriam Merad
Mapped how macrophages and dendritic cells in tumours suppress immunity, opening new immunotherapy targets.
Immunologist who defined tissue-resident macrophage biology and used single-cell atlases of lung tumours to identify myeloid programmes (e.g. TREM2) that shape response to immunotherapy; AAI president.
Role
Director, Marc and Jennifer Lipschultz Precision Immunology Institute; Chair, Department of Immunology and Immunotherapy
Specialisms
Myeloid cellsTumour-associated macrophagesSingle-cell immunology
Profiles
| Title | Journal | Year |
|---|---|---|
| Innate immune landscape in early lung adenocarcinoma by paired single-cell analyses | Cell | 2017 |
Pages like this
not linked directly; found by shared links- PersonThomas U. Marron
Shares The Mount Sinai Hospital / Tisch Cancer Institute, Hepatocellular carcinoma.
- PersonWoong-Yang Park
Shares Single-cell & spatial profiling, Non-small-cell lung cancer.
- IdeaStandards for spatial and multiplex tissue biomarkers before they reach the clinic
Shares Hot vs cold tumours, Single-cell & spatial profiling.
- IdeaMap which tumour clones sit next to which immune cells before choosing therapy
Shares Hot vs cold tumours, Single-cell & spatial profiling.
- TermSTK11 / KEAP1 co-mutations
- IdeaClear the suppressive neutrophils out of pancreatic tumours first
Shares Hot vs cold tumours, Single-cell & spatial profiling.
- IdeaBlock the complement signal that recruits tumour-protecting cells
- IdeaTurn one tumour into a vaccine to treat all the others
Shares The Mount Sinai Hospital / Tisch Cancer Institute, Hot vs cold tumours.