Weiping Zou
Immunologist who showed PD-L1 on tumours suppresses T cells and linked interferon to ferroptosis.
Defined immunosuppressive mechanisms in the tumour microenvironment, including B7-H1/PD-L1 and myeloid suppression, and showed CD8 T cells drive tumour ferroptosis.
| Title | Journal | Year |
|---|---|---|
| CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy | Nature | 2019 |
Pages like this
not linked directly; found by shared links- ProductCosibelimab
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- PersonDrew M. Pardoll
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- Key paperIwai and Honjo: tumours use PD-L1 to escape T cells, and blocking it restores attack
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- PathwayJAK–STAT signalling
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- TermImmune checkpoint
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- TermHallmark: avoiding immune destruction
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- CancerGestational trophoblastic neoplasia
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.
- PathwayThe cancer-immunity cycle
Shares PD-1 / PD-L1 immune checkpoint & T-cell activation, PD-L1.