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Living with cancer· Appointment prep

Appointment sheet: Platinum-resistant ovarian cancer

One page to bring and write on: your details, the questions for Platinum-resistant ovarian cancer plus your own, the words you may hear, what to bring, the treatments the standard of care names, and room for the answers and agreed next steps. What you type stays in this browser. Print it or save it as a PDF. New to all this? Start with the first 60 days. Orientation, not medical advice.

Tick the questions to print

All of this cancer's questions start ticked. Untick what does not apply; ticks are kept in this browser. .

Your own questions

Shared with the prep pack, so questions you add there appear here too.

Print or save as PDF

Use (or Ctrl+P, Cmd+P on a Mac). To keep a copy, choose Save as PDF as the destination in the print dialog. Only the sheet prints; the controls stay on screen. Your typed notes print where you typed them; empty fields print as ruled lines to write on.

Appointment sheet

Platinum-resistant ovarian cancer

Prepared with OnCo (onco.cc/prep/platinum-resistant-ovarian-cancer/). Orientation, not medical advice; your team knows your case.

My details

Name
Date of appointment
Hospital and clinician
Who is coming with me

What I know, what is unclear, changes to discuss

Saved in this browser
What I know so far
What is unclear to me
Changes since last time

My questions

22 on the sheet
Newly diagnosed
  1. 1.What is my exact diagnosis, stage, and grade, and which tests established them?
  2. 2.Which biomarkers have been tested on my tumour (for example Platinum-free interval under six months, Folate receptor alpha immunohistochemistry, PD-L1 combined positive score, Prior bevacizumab and PARP inhibitor exposure, CDH6, B7-H4 and TROP2 expression), and what were the results?
  3. 3.Which subtype is my cancer, and does that change the recommended treatment?
  4. 4.Is germline (inherited) genetic testing recommended for me or my family?
Folate receptor alpha-high
  1. 5.For my situation (folate receptor alpha-high), which of the standard options do you recommend and why?
  2. 6.Am I a candidate for Mirvetuximab soravtansine, and what side effects should I expect?
  3. 7.How do the results of MIRASOL / GOG-3045 apply to someone like me?
PD-L1 CPS 1 or more
  1. 8.For my situation (pd-l1 cps 1 or more), which of the standard options do you recommend and why?
  2. 9.Am I a candidate for Pembrolizumab, Paclitaxel / nab-paclitaxel, Bevacizumab, and what side effects should I expect?
  3. 10.How do the results of KEYNOTE-B96 / ENGOT-ov65 apply to someone like me?
Any expression status
  1. 11.For my situation (any expression status), which of the standard options do you recommend and why?
  2. 12.Am I a candidate for Relacorilant, Paclitaxel / nab-paclitaxel, Pegylated liposomal doxorubicin or related drugs, and what side effects should I expect?
  3. 13.How do the results of ROSELLA / GOG-3073 apply to someone like me?
Later lines
  1. 14.For my situation (later lines), which of the standard options do you recommend and why?
  2. 15.Am I a candidate for Raludotatug deruxtecan, Rinatabart sesutecan, Luveltamab tazevibulin or related drugs, and what side effects should I expect?
  3. 16.How do the results of REJOICE-Ovarian01 and RAINFOL-01 (Rina-S) apply to someone like me?
Supportive care
  1. 17.For my situation (supportive care), which of the standard options do you recommend and why?
Any stage
  1. 18.Are there clinical trials I could join, for example of Raludotatug deruxtecan, REJOICE-Ovarian01, Rinatabart sesutecan, RAINFOL-01 (Rina-S)?
  2. 19.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
  3. 20.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
  4. 21.I read that “Sequencing antibody-drug conjugates that share topoisomerase or tubulin payloads”. How does that affect my plan?
  5. 22.I read that “Whether platinum resistance can be reversed rather than bypassed”. How does that affect my plan?

Tests and results to bring

Biomarker results to ask for: Platinum-free interval under six months, Folate receptor alpha immunohistochemistry (high expression required for mirvetuximab), PD-L1 combined positive score (pembrolizumab), Prior bevacizumab and PARP inhibitor exposure, CDH6, B7-H4 and TROP2 expression (antibody-drug conjugate trials), BRCA reversion mutations, CA-125 and imaging for response.

Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.

The treatments I may be offered

From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.

Answers and next steps

Saved in this browser
What I was told
Agreed next steps, dates and who to call