Loading
CD163 marks the macrophages that help a tumour rather than attack it. It is the usual way of counting those cells in a tumour sample, which is why it appears whenever tumour-associated macrophages are discussed.
CD163 is a scavenger receptor for haemoglobin-haptoglobin complexes and is confined to monocytes and macrophages. It is the marker most often used to identify alternatively activated macrophages, the phenotype associated with tissue repair and immune suppression rather than with killing, and so it is the standard stain for counting tumour-associated macrophages in a tissue section. A soluble form shed into blood is measured in inflammatory disease. CD163 is the practical link between the macrophage record on this site and the agents aimed at that compartment, such as the CSF1R antibodies.
In plain words · CD163 marks the macrophages that help a tumour rather than attack it. It is the usual way of counting those cells in a tumour sample, which is why it appears whenever tumour-associated macrophages are discussed.
CD163 marks the macrophages that help a tumour rather than attack it. It is the usual way of counting those cells in a tumour sample, which is why it appears whenever tumour-associated macrophages are discussed.
Scavenger receptor for haemoglobin-haptoglobin complexes, restricted to the monocyte and macrophage line.
No product in this corpus aims at CD163 yet. Because it sits on the outside of the cell, it can be reached from the bloodstream: antibodies flag the cell, ADCs deliver a toxin, radioligands deliver radiation, and CAR-T or bispecifics bring a T cell.
Scavenger receptor for haemoglobin-haptoglobin complexes, restricted to the monocyte and macrophage line.
Query for this target: (TITLE:"CD163" OR ABSTRACT:"CD163") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about CD163, not a curated reading list.
Shares Tumour microenvironment (TME) and the tag immune-marker.
Shares Tumour-associated macrophages (TAMs), CSF1R, Tumour microenvironment (TME).
Shares CD14, Tumour microenvironment (TME).
Shares Tumour-associated macrophages (TAMs), CSF1R, Tumour microenvironment (TME).
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/