AI scoring of biomarkers and grade on pathology slides
Software that reads digitised biopsy slides to detect cancer, grade it, and score biomarkers such as HER2, PD-L1 and Ki-67 more consistently than the eye alone.
Overview
Deep-learning models trained on whole-slide images now detect prostate cancer in biopsies (Paige Prostate, the first FDA-authorised AI pathology tool, 2021), assist Gleason grading, count mitoses, and quantify immunohistochemistry such as HER2, PD-L1 and Ki-67, where pathologist agreement is known to be poor at the decision thresholds. Newer models infer molecular states, such as microsatellite instability, directly from routine H&E slides.
How it works
Convolutional or transformer networks trained on annotated whole-slide images produce per-region probabilities that are aggregated into detections, grades or scores presented to the pathologist.
- Reduces scoring variability at treatment thresholds
- Triages slides and flags missed foci
- Can infer molecular features from H&E alone
- Performance depends on scanner and stain domain
- Regulatory clearance is product by product
- Pathologist remains responsible for the diagnosis
Latest papers
topQuery for this technology: (TITLE:"AI scoring of biomarkers and grade on pathology slides" OR ABSTRACT:"AI scoring of biomarkers and grade on pathology slides") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about AI scoring of biomarkers and grade on pathology slides, not a curated reading list.
Similar pages
not linked directly; found by shared links- CompanyIbex Medical Analytics
Shares Digital pathology & AI, HER2-positive breast cancer, Prostate cancer.
- CompanyX-Zell
Shares Digital pathology & AI, Prostate cancer.
- CompanyPerimeter Medical Imaging AI
- PersonThomas J. Fuchs
Shares Digital pathology & AI, Prostate cancer.
- PairingAI pathology → androgen deprivation duration
Shares Digital pathology & AI, Prostate cancer.
- TreatmentPaige Prostate Detect
Shares Digital pathology & AI, Prostate cancer.
- IdeaReal-time margin assessment and image-guided surgery as the global standard
Shares Digital pathology & AI, Prostate cancer.
- CompanyAtaraxis AI