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Lycopene is the red pigment in tomatoes, sold as a supplement to prevent prostate cancer. People who eat more tomatoes have lower rates of some cancers, but trials of lycopene supplements have not shown that they prevent or treat prostate cancer.
Lycopene is a carotenoid that, unlike beta-carotene, is not converted to vitamin A. Memorial Sloan Kettering's About Herbs summary reports that observational studies associate higher lycopene intake with lower risk of several cancers, especially prostate, but that supplementation trials do not show prevention: lycopene or tomato-based regimens did not prevent prostate cancer; a lycopene-rich extract gave no benefit in men with high-grade prostatic intraepithelial neoplasia; and high doses of lycopene combined with green tea catechins and selenium were associated with more prostate cancer. Results in men with prostate cancer are variable, and an early report of docetaxel plus lycopene in castration-resistant disease needs testing in a proper trial. MSK notes poor quality control: in six commercial brands, lycopene content differed from the label by up to 43 per cent. Lycopene is generally safe; very high intake from tomato products can turn the skin orange. Eating tomatoes as part of a plant-rich diet is reasonable; capsules have no proven advantage.
An antioxidant carotenoid that concentrates in prostate tissue; the link between dietary intake and lower risk may reflect overall diet rather than lycopene itself.
Query for this technology: (TITLE:"Lycopene" OR ABSTRACT:"Lycopene" OR TITLE:"Non-provitamin A carotenoid" OR ABSTRACT:"Non-provitamin A carotenoid") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Lycopene, not a curated reading list.
Shares Mediterranean and plant-forward dietary patterns, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Mediterranean and plant-forward dietary patterns, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
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Shares Evidence-based integrative oncology, Misinformation and unproven therapies, Prostate cancer and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Misinformation and unproven therapies, Prostate cancer and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
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