Loading
The laboratory machines that find and measure the abnormal antibody (M-protein) made by myeloma cells in a blood sample, used to diagnose myeloma and related conditions and to follow treatment.
The Binding Site's EXENT analyser with its immunoglobulin isotypes (GAM) assay was cleared on 17 October 2025 (K250159) under a new mass spectrometric immunoglobulin code (SGG); the assay is "an aid in the evaluation of monoclonal gammopathy of undetermined significance (MGUS); and as an aid in the diagnosis of smouldering multiple myeloma (SMM), multiple myeloma (MM), Waldenström's macroglobulinaemia, and AL amyloidosis". Sebia's Capillarys 3 Tera with CAPI 3 immunotyping (K192095, 1 November 2019, code CFF) performs capillary electrophoresis. The Binding Site's free light chain assays on its Optilite analyser include Freelite kappa and lambda (K231290, 24 January 2024), Freelite Mx (K250549, 23 May 2025) and the Hevylite IgG kappa and lambda heavy and light chain kits (K172613, 15 February 2018). The glossary entry on M-protein and free light chains explains the tests.
Immunoglobulins are enriched with antibody-coated beads and their light chains measured by mass (matrix-assisted laser desorption ionisation time of flight), separated by charge in a capillary, or quantified by nephelometric immunoassay for free light chains.
Query for this technology: (TITLE:"M-protein analysers: mass spectrometry, capillary electrophoresis and free light chain assays" OR ABSTRACT:"M-protein analysers: mass spectrometry, capillary electrophoresis and free light chain assays" OR TITLE:"EXENT, Capillarys, Freelite" OR ABSTRACT:"EXENT, Capillarys, Freelite" OR TITLE:"EXENT" OR ABSTRACT:"EXENT" OR TITLE:"MALDI-TOF M-protein" OR ABSTRACT:"MALDI-TOF M-protein") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about M-protein analysers: mass spectrometry, capillary electrophoresis and free light chain assays (EXENT, Capillarys, Freelite), not a curated reading list.
Shares Haematology analysers and digital blood film and marrow morphology (Sysmex XN, DxH 900, CellaVision, Scopio) and the tag devices-gaps-2026-11.
Shares Automated analysers for tumour-marker blood tests (Elecsys, Atellica, Access, VITROS, Lumipulse), Haematology analysers and digital blood film and marrow morphology (Sysmex XN, DxH 900, CellaVision, Scopio).
Shares Powered bone marrow biopsy drivers (OnControl, BD Trek, OmniBone), Haematology analysers and digital blood film and marrow morphology (Sysmex XN, DxH 900, CellaVision, Scopio), Multiple myeloma.
Shares M-protein, immunofixation and serum free light chains, Multiple myeloma.
Every source this page cites, grouped by who published it. Grouping is read from the web address, not assigned by hand.
A source that has moved or gone is reported by the weekly link check. /audit/