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Pau d'arco is a South American tree bark tea sold to treat infections and cancer. Its main ingredient, lapachol, had no effect in people with chronic myeloid leukaemia, and in animals large doses caused anaemia and harmed unborn young. It may add to blood thinners.
Pau d'arco comes from the inner bark of Tabebuia (Handroanthus) trees and is drunk as a tea or sold as tablets marketed for infections and cancer. Memorial Sloan Kettering's About Herbs summary lists antibacterial, antifungal, anti-inflammatory, anticoagulant and anticancer effects in laboratory and animal work and says human studies are needed to validate them. Preliminary findings suggest it may help prevent oral mucositis during head and neck radiotherapy, but lapachol, an active constituent, had no clinical effect in patients with chronic myelocytic leukaemia. A clinical study reported nausea, vomiting and discoloured urine; in animals, large chronic doses of lapachol caused anaemia, reproductive and fetotoxic effects and chromosomal abnormalities. Pau d'arco may increase the activity of anticoagulant and antiplatelet drugs.
Naphthoquinones such as lapachol and beta-lapachone are cytotoxic in cell culture and interfere with vitamin K-dependent clotting.
Query for this technology: (TITLE:"Pau d'arco" OR ABSTRACT:"Pau d'arco" OR TITLE:"lapacho, taheebo" OR ABSTRACT:"lapacho, taheebo") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Pau d'arco (lapacho, taheebo), not a curated reading list.
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Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
Shares Unproven diet claims (alkaline, juice, 'anti-cancer' diets), Dietary supplements during cancer treatment: interactions and harms, Evidence-based integrative oncology, Misinformation and unproven therapies and the tags complementary, supportive-care.
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