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Energy balance

aka Energy balance and cancer, Physical activity, diet and adiposity

The umbrella term researchers use for the combined effect of what you eat, how much you move and how much fat you carry. It is the framework linking diet, exercise and obesity research to cancer.

Energy balance research treats diet, physical activity and adiposity as one system acting through shared pathways (insulin, IGF-1, sex steroids, adipokines, inflammation, immune function). It underlies the design of trials such as CHALLENGE and BWEL and the NCI's Transdisciplinary Research on Energetics and Cancer programme. Its practical implication is that interventions on any one arm are confounded by, and may need to be combined with, the others.

Category
Nutrition & lifestyle

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