Hot flushes on hormone therapy

They range from under three minutes of feeling warm to hours of sweating that needs a change of clothes or bedding, and they often disturb sleep. NICE NG131 offers medroxyprogesterone 20 mg a day for an initial 10 weeks and then evaluates it, with cyproterone acetate 50 mg twice a day for 4 weeks as the second option. In a randomised trial of 309 men, the median daily hot-flush score fell by 83.7 percent on medroxyprogesterone, 94.5 percent on cyproterone and 47.2 percent on venlafaxine at one month.