Loading
Spatial platforms measure RNA or protein while keeping each measurement's position on the tissue slide, so cell types and gene programmes can be mapped onto the tumour's architecture.
Spatial transcriptomics captures the positional context of transcription within intact tissue (Wikipedia). The platforms differ in what they trade: 10x Visium captures whole-transcriptome RNA on barcoded spots (55 micron spots originally, 2 micron bins in Visium HD); Xenium, MERFISH and CosMx image a targeted panel of hundreds to thousands of genes in situ at single-cell and subcellular resolution; CODEX (now PhenoCycler) cycles antibodies to image dozens of proteins. Public sections from 10x are CC BY 4.0 and are the usual first test for spatial models, and HTAN is assembling multi-platform tumour atlases.
Showing the technology this term belongs to: Spatial transcriptomics.
Shares Spatial autocorrelation (Moran's I), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Single-cell RNA sequencing (scRNA-seq, 10x Chromium), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Spatial transcriptomics, Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Spatially aware clustering (SpaGCN, KNN smoothing), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Single-cell RNA sequencing (scRNA-seq, 10x Chromium), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Single-cell RNA sequencing (scRNA-seq, 10x Chromium), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Single-cell RNA sequencing (scRNA-seq, 10x Chromium), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.
Shares Single-cell RNA sequencing (scRNA-seq, 10x Chromium), Cancer AI vocabulary (CanSim terms map) and the tag cansim-terms.