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The study that proved a scan can tell, before any surgery, whether the surgeon will get all of a rectal cancer out, which is why every rectal cancer in the NHS now gets an MRI first.
MERCURY tested whether high-resolution magnetic resonance imaging could predict the circumferential resection margin, the single strongest predictor of local recurrence after rectal cancer surgery. Of 408 patients, 354 (87 percent) had a clear margin at histopathology. Where the scan predicted a clear margin it was right in 327 of 349 cases (94 percent), and specificity for a clear margin was 92 percent. High-resolution scans were technically satisfactory in 93 percent, and the technique reproduced across centres. That reproducibility is what made MRI staging a national standard: it lets the multidisciplinary team decide before the operation who needs radiotherapy first, which is the decision CR07 and STAR-TREC then refined.
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Shares The Royal Marsden, Colorectal cancer and the tag uk.
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