Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?

Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer? is a phase 2/3, randomised interventional study registered as NCT02945566 by University of Birmingham, with a registry enrolment figure of 380 participants, started 2017-06-14 and due to reach its primary completion in 2027-08. Interventions recorded: Standard TME surgery; Long course concurrent chemoradiation with capecitabine and radiotherapy; Short course radiotherapy. Conditions listed: Adenocarcinoma of the Rectum. Primary outcome: Phase II (Feasibility study) Primary Outcome: Recruitment Rate; Phase III Primary Outcome: Organ Preservation. Colorectal eligibility wording from the registry: "* Biopsy proven adenocarcinoma of the rectum". Sites: Belgium, Denmark, Netherlands, Sweden, United Kingdom. United Kingdom sites listed: 1. No results are recorded here; the registry entry is the source.