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A phase 3 trial of atezolizumab, carboplatin, cisplatin and etoposide in lung cancer, run by National Cancer Institute (NCI), active but no longer recruiting.
Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC) is a phase 3, randomised interventional study registered as NCT03811002 by National Cancer Institute (NCI), with a registry enrolment figure of 544 participants, started 2019-07-26 and due to reach its primary completion in 2024-04-21. Interventions recorded: 3-Dimensional Conformal Radiation Therapy; Atezolizumab; Biospecimen Collection; Carboplatin; Cisplatin; Etoposide; Intensity-Modulated Radiation Therapy; Quality-of-Life Assessment; Questionnaire Administration. Conditions listed: Limited Stage Lung Small Cell Carcinoma; Stage I Lung Cancer AJCC v8; Stage II Lung Cancer AJCC v8; Stage III Lung Cancer AJCC v8. Primary outcome: Overall Survival. Lung eligibility wording from the registry: "* Pathologically (histologically or cytologically) proven diagnosis of limited stage small cell lung cancer (Stage Tx, T1-T4, N0-3, M0, American Joint Committee on Cancer \[AJCC\] staging, 8th edition \[Ed". Sites: Japan, United States. No results are recorded here; the registry entry is the source.
Shares Limited-stage small-cell lung cancer, Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Atezolizumab, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Atezolizumab, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Atezolizumab, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Lung cancer trials open today (registry snapshot), Cisplatin, Platinum agents, Carboplatin and the tag lung-deep-dive.