A phase 1/2 trial of carboplatin, atezolizumab and etoposide in lung cancer, run by Vanderbilt-Ingram Cancer Center, now recruiting.
Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation is a phase 1/2, interventional study registered as NCT06110572 by Vanderbilt-Ingram Cancer Center, with a registry enrolment figure of 18 participants, started 2024-04-24 and due to reach its primary completion in 2027-06-30. Interventions recorded: Carboplatin; Atezolizumab; Etoposide; Total Body Irradiation; Hypofractionated Radiation Therapy; Magnetic Resonance Imaging. Conditions listed: Extensive Stage Lung Small Cell Carcinoma; Stage IV Lung Cancer. Primary outcome: Rates of treatment-related adverse events; Progression-free survival. Lung eligibility wording from the registry: "* Histologically documented or cytologically confirmed diagnosis of extensive stage small-celllung cancer with evaluable disease per RECIST v1". Sites: United States. No results are recorded here; the registry entry is the source.
Shares Extensive-stage small-cell lung cancer, Etoposide, Atezolizumab, Topoisomerase-I inhibitors (and ADC payloads) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Atezolizumab, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.
Shares Atezolizumab, Lung cancer trials open today (registry snapshot), Platinum agents, Carboplatin and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Atezolizumab, Lung cancer trials open today (registry snapshot), Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Platinum agents and the tag lung-deep-dive.