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A phase 2 trial of adebrelimab, carboplatin, cisplatin and etoposide in lung cancer, run by Nanfang Hospital, Southern Medical University, now recruiting.
A Phase II Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLC is a phase 2, interventional study registered as NCT06177925 by Nanfang Hospital, Southern Medical University, with a registry enrolment figure of 62 participants, started 2023-12-10 and due to reach its primary completion in 2026-06-30. Interventions recorded: Adebrelimab; Carboplatin/Cisplatin; Etoposide; Radiation therapy. Conditions listed: Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Carcinoma, Bronchogenic; Bronchial Neoplasms; Lung Neoplasms; Small Cell Lung Carcinoma. Primary outcome: Progression-Free Survival (PFS). Lung eligibility wording from the registry: "* Histologically or cytologically confirmed ES-SCLC (per the Veterans Administration Lung Study Group \[VALG\] staging system)，the number of metastatic lesions ≤ 5, the number of metastatic organs ≤ 3, and no previous systemic chemotherapy, radiotherapy or immune checkpoint inhibitor treatment". Sites: China. No results are recorded here; the registry entry is the source.
Shares Extensive-stage small-cell lung cancer, Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot), Cisplatin and the tag lung-deep-dive.
Shares Extensive-stage small-cell lung cancer, Etoposide, Topoisomerase-I inhibitors (and ADC payloads), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Adebrelimab, Extensive-stage small-cell lung cancer, Lung cancer trials open today (registry snapshot), IMRT / IGRT (modern external beam) and the tag lung-deep-dive.