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A phase 1/2 trial in pancreatic cancer, run by National Cancer Institute (NCI), now recruiting.
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer is a phase 1/2, randomised interventional study registered as NCT04172532 by National Cancer Institute (NCI), with a registry enrolment figure of 92 participants, started 2021-01-11 and due to reach its primary completion in 2027-08-01. Interventions recorded: Biopsy Procedure; Biospecimen Collection; Computed Tomography; Hypofractionated Radiation Therapy; Magnetic Resonance Imaging; Peposertib; Placebo Administration. Conditions listed: Locally Advanced Pancreatic Adenocarcinoma; Stage III Pancreatic Cancer AJCC v8. Primary outcome: Maximum tolerated dose (Phase I); Recommended phase 2 dose (Phase I); Progression-free survival rate (Phase II). Pancreatic eligibility wording from the registry: "* Patients must have pathologically confirmed pancreatic adenocarcinoma". Sites: United States. No results are recorded here; the registry entry is the source.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), IMRT / IGRT (modern external beam) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), IMRT / IGRT (modern external beam) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), IMRT / IGRT (modern external beam) and the tag pancreatic-deep-dive.