Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation
A phase 2 trial of Adagrasib, Pembrolizumab, Pemetrexed, Carboplatin and Cisplatin in non-small-cell lung cancer, run by Mirati Therapeutics Inc., active and no longer recruiting.
Overview
Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation is a phase 2 interventional study registered as NCT05609578 by Mirati Therapeutics Inc., with 90 participants enrolled, started 2022-11-22 and due to reach its primary completion in 2026-09-30. Interventions recorded: Adagrasib oral dose of 400 mg twice daily tablets, Pembrolizumab, Chemotherapy: Pemetrexed and Cisplatin/Carboplatin.
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