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A phase 2 trial of trastuzumab deruxtecan, durvalumab, panitumumab, botensilimab and other drugs in colorectal cancer, run by Gruppo Oncologico del Nord-Ovest, now recruiting.
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN) is a phase 2, interventional study registered as NCT05845450 by Gruppo Oncologico del Nord-Ovest, with a registry enrolment figure of 197 participants, started 2023-05-11 and due to reach its primary completion in 2027-05. Interventions recorded: Trastuzumab deruxtecan; Durvalumab; Panitumumab; Botensilimab; Balstilimab; Sotorasib; Vorbipiprant; Nivolumab; Amivantamab; Botensilimab; Balstilimab. Conditions listed: Colorectal Cancer; Resectable Colorectal Carcinoma. Primary outcome: major pathological response rate. Colorectal eligibility wording from the registry: "* Histologically confirmed colorectal cancer adenocarcinoma that is judged as initially resectable with elective surgery aimed at radical intent with R0 margins as per multidisciplinary team assessment". Sites: Italy. No results are recorded here; the registry entry is the source.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.