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A phase 2 trial of balstilimab and botensilimab in colorectal cancer, run by Darren Sigal, MD, now recruiting.
BAL/BOT/agenT-797 in pMMR CRC With Liver Metastases is a phase 2, interventional study registered as NCT07550088 by Darren Sigal, MD, with a registry enrolment figure of 17 participants, started 2026-06-10 and due to reach its primary completion in 2028-09. Interventions recorded: Balstilimab (BAL); Botensilimab (BOT); agenT-797. Conditions listed: Colorectal Cancer Metastatic. Primary outcome: Overall Response Rate (ORR). Colorectal eligibility wording from the registry: "* Adults ≥18 years of age with histologically confirmed metastatic colorectal cancer with liver metastases, including evidence of active liver disease if previously treated locally". Sites: United States. No results are recorded here; the registry entry is the source.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Botensilimab, Balstilimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.