Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer

Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer is a phase 3, randomised interventional study registered as NCT06097416 by St. James's Hospital, Ireland, with a registry enrolment figure of 100 participants, started 2024-10 and due to reach its primary completion in 2025-10. Interventions recorded: Neoadjuvant Chemoradiotherapy; Total Neoadjuvant Therapy. Conditions listed: Rectal Cancer. Primary outcome: Overall survival. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed surgically resectable adenocarcinoma of the rectum". No results are recorded here; the registry entry is the source.