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A phase 2 trial of adagrasib in lung cancer, run by Ryan Gentzler, MD, now recruiting.
Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases is a phase 2, interventional study registered as NCT06248606 by Ryan Gentzler, MD, with a registry enrolment figure of 30 participants, started 2024-08-06 and due to reach its primary completion in 2027-02-25. Interventions recorded: Adagrasib; Stereotactic Radiosurgery. Conditions listed: Non Small Cell Lung Cancer; NSCLC; KRAS G12C. Primary outcome: Intracranial disease control rate (DCR). Lung eligibility wording from the registry: "Confirmation of stage IV non-small cell lung cancer (NSCLC) per AJCC, 8th edition, or metastatic recurrence after treatment for earlier stage disease". Sites: United States. No results are recorded here; the registry entry is the source.
Shares KRAS G12C-mutant non-small-cell lung cancer, KRAS & RAS inhibitors, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares KRAS G12C-mutant non-small-cell lung cancer, KRAS & RAS inhibitors, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares Bristol Myers Squibb, SBRT / SABR (stereotactic radiotherapy), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares KRAS G12C-mutant non-small-cell lung cancer, KRAS & RAS inhibitors, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares KRAS G12C-mutant non-small-cell lung cancer, Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.
Shares SBRT / SABR (stereotactic radiotherapy), Lung cancer trials open today (registry snapshot) and the tag lung-deep-dive.