Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain is a phase 3, randomised interventional study registered as NCT06500455 by NRG Oncology, with a registry enrolment figure of 274 participants, started 2024-12-12 and due to reach its primary completion in 2028-06-30. Interventions recorded: Computed Tomography; Fractionated Stereotactic Radiation Therapy; Magnetic Resonance Imaging; Stereotactic Radiosurgery. Conditions listed: Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Breast Carcinoma; Metastatic Digestive System Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Neoplasm in the Brain; Metastatic Malignant Solid Neoplasm; Metastatic Melanom. Primary outcome: Time to local failure. Lung eligibility wording from the registry: "* Non-small cell lung cancer". Sites: Canada, Hong Kong, Ireland, United States. No results are recorded here; the registry entry is the source.