Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction is a phase 2, randomised interventional study registered as NCT07132190 by Ayal A. Aizer, MD, with a registry enrolment figure of 60 participants, started 2025-12-30 and due to reach its primary completion in 2028-09. Interventions recorded: Linear accelerator-based stereotactic radiation for brain metastases using 0mm or 1mm PTV. Conditions listed: Brain Metastases, Adult; Brain Tumor - Metastatic; Brain Metastases From Non-small Cell Lung Cancer (NSCLC); Brain Metastases From Extra-cranial Solid Tumors. Primary outcome: To assess the percentage of patients that demonstrate tumor beyond the standard planning margin (1.0mm PTV) at the time of stereotactic treatment.. Sites: United States. No results are recorded here; the registry entry is the source.