Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurre

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer is a phase 1/2, interventional study registered as NCT06307548 by Roswell Park Cancer Institute, with a registry enrolment figure of 21 participants, started 2024-07-30 and due to reach its primary completion in 2027-06-01. Interventions recorded: Aminolevulinic Acid; Biospecimen Collection; Computed Tomography; Fluorescence-Guided Surgery; Magnetic Resonance Imaging; Photodynamic Therapy; Surgical Procedure. Conditions listed: Locally Advanced Colorectal Carcinoma; Recurrent Colorectal Carcinoma; Stage III Colorectal Cancer. Primary outcome: Accuracy of the fluorescence imaging (Phase I); Incidence of adverse events (Phase I); Evidence of disease (Phase II). Colorectal eligibility wording from the registry: "* Patients with locally advanced or recurrent colorectal cancer undergoing surgery". Sites: United States. No results are recorded here; the registry entry is the source.