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A phase 3 trial of cAPOX (capecitabine, oxaliplatin), fOLFIRI (5-FU, leucovorin, irinotecan), fLOT (5-FU, leucovorin, oxaliplatin, docetaxel), fluorouracil (5-FU) and other drugs in pancreatic cancer, run by Gruppo Oncologico del Nord-Ovest, now recruiting.
Gemcitabine Plus Nab-paclitaxel as Switch Maintenance Versus Continuation of Modified FOLFIRINOX as 1st Line Chemotherapy in Patients With Advanced Pancreatic Cancer. is a phase 3, randomised interventional study registered as NCT06897644 by Gruppo Oncologico del Nord-Ovest, with a registry enrolment figure of 340 participants, started 2025-03-27 and due to reach its primary completion in 2029-01-01. Interventions recorded: Oxaliplatin; Irinotecan (CPT-11); Leucovorin; 5-FU (5-fluorouracil); gemcitabine; Nab-paclitaxel. Conditions listed: Pancreatic Adenocarcinoma Advanced or Metastatic. Primary outcome: Overall Survival (OS). Pancreatic eligibility wording from the registry: "* Histologically or cytologically confirmed unresectable locally advanced or metastatic pancreatic adenocarcinoma eligible for treatment in the first-line setting". Sites: Italy. No results are recorded here; the registry entry is the source.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), CAPOX (capecitabine, oxaliplatin), Nab-paclitaxel and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), Nab-paclitaxel, Fluorouracil (5-FU) and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), CAPOX (capecitabine, oxaliplatin), Nab-paclitaxel and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Nab-paclitaxel, Fluorouracil (5-FU), Locally advanced unresectable pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), CAPOX (capecitabine, oxaliplatin), Fluorouracil (5-FU), Locally advanced unresectable pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine and the tag pancreatic-deep-dive.
Shares Nab-paclitaxel, Locally advanced unresectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites), Gemcitabine and the tag pancreatic-deep-dive.