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A phase 2 trial of fluorouracil (5-FU), gemcitabine, fOLFIRI (5-FU, leucovorin, irinotecan), fLOT (5-FU, leucovorin, oxaliplatin, docetaxel) and other drugs in pancreatic cancer, run by Northwestern University, not yet recruiting.
SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial is a phase 2, interventional study registered as NCT07748611 by Northwestern University, with a registry enrolment figure of 125 participants, started 2027-02-03 and due to reach its primary completion in 2030-02-03. Interventions recorded: Biospecimen Collection; Computed Tomography; Electronic Health Record Review; Fluorouracil; Gemcitabine; Irinotecan; Leucovorin; Magnetic Resonance Imaging; Nab-paclitaxel; Oxaliplatin; Radiation Therapy; Surgical Procedure. Conditions listed: Borderline Resectable Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma. Primary outcome: Proportion of patients who achieve R0/R1 surgical resection (Cohort A). Pancreatic eligibility wording from the registry: "* Patients must have histologically confirmed pancreas ductal adenocarcinoma". Sites: United States. No results are recorded here; the registry entry is the source.
Shares FOLFIRI (5-FU, leucovorin, irinotecan), CAPOX (capecitabine, oxaliplatin), Borderline resectable pancreatic ductal adenocarcinoma, Nab-paclitaxel and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), CAPOX (capecitabine, oxaliplatin), Nab-paclitaxel and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), CAPOX (capecitabine, oxaliplatin), Nab-paclitaxel and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), CAPOX (capecitabine, oxaliplatin), Borderline resectable pancreatic ductal adenocarcinoma, Resectable pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.
Shares Borderline resectable pancreatic ductal adenocarcinoma, Nab-paclitaxel, Resectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), CAPOX (capecitabine, oxaliplatin), Borderline resectable pancreatic ductal adenocarcinoma, Fluorouracil (5-FU) and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), FOLFIRI (5-FU, leucovorin, irinotecan), Nab-paclitaxel, Fluorouracil (5-FU) and the tag pancreatic-deep-dive.
Shares Borderline resectable pancreatic ductal adenocarcinoma, Nab-paclitaxel, Resectable pancreatic ductal adenocarcinoma, Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.