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A phase 3 trial of tepotinib, pemetrexed, vinorelbine, docetaxel and other drugs in lung cancer, run by Intergroupe Francophone de Cancerologie Thoracique, now recruiting.
Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated is a phase 3, randomised interventional study registered as NCT06908993 by Intergroupe Francophone de Cancerologie Thoracique, with a registry enrolment figure of 133 participants, started 2025-12-09 and due to reach its primary completion in 2028-03-15. Interventions recorded: Tepotinib; Pemetrexed (Alimta); Vinorelbine; Gemcitabine alone; Docetaxel; Paclitaxel; Pembrolizumab; Nivolumab; Atezolizumab. Conditions listed: Advanced Non Small Cell Lung Cancer; MET Exon 14 Mutation. Primary outcome: Progression-Free Survival (PFS). Lung eligibility wording from the registry: "Histologically proven advanced NSCLC". Sites: France. No results are recorded here; the registry entry is the source.
Shares Vinorelbine, Atezolizumab, Docetaxel, Pemetrexed and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel, Pembrolizumab and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Pembrolizumab, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel, Pembrolizumab and the tag lung-deep-dive.
Shares Pemetrexed, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel, Pembrolizumab and the tag lung-deep-dive.
Shares Atezolizumab, Pemetrexed, Lung cancer trials open today (registry snapshot), Nivolumab and the tag lung-deep-dive.
Shares Atezolizumab, Lung cancer trials open today (registry snapshot), Paclitaxel / nab-paclitaxel, Cytotoxic chemotherapy and the tag lung-deep-dive.
Shares MET exon 14 and MET-amplified non-small-cell lung cancer, Docetaxel, Lung cancer trials open today (registry snapshot), Cytotoxic chemotherapy and the tag lung-deep-dive.