Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer

Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer is a phase 2, randomised interventional study registered as NCT07154316 by Fudan University, with a registry enrolment figure of 138 participants, started 2025-08-01 and due to reach its primary completion in 2028-08-01. Interventions recorded: LCRT; SCRT; CAPOX; PD-1; Celecoxib. Conditions listed: Colorectal Cancer. Primary outcome: CR (Complete Response). Colorectal eligibility wording from the registry: "* Pathologically confirmed rectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.