Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer

Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer is a phase 2, randomised interventional study registered as NCT07200141 by Peking Union Medical College Hospital, with a registry enrolment figure of 156 participants, started 2025-10-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: GTV 58.75 Gy/25 fractions(Simultaneous Integrated Boost); GTV 50 Gy/25 fractions(Simultaneous Integrated Boost); Concurrent Chemotherapy; Total mesorectal excision (TME) surgery or non-operative management. Conditions listed: Locally Advanced Rectal Adenocarcinoma. Primary outcome: CR. Colorectal eligibility wording from the registry: "Histologically confirmed rectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.