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A phase 1/2 trial of ivonescimab in colorectal cancer, run by Akeso, not yet recruiting.
A Study of AK112 in Combination With VG2025 in Colorectal Cancer With Liver Metastases is a phase 1/2, randomised interventional study registered as NCT07357220 by Akeso, with a registry enrolment figure of 72 participants, started 2026-03-02 and due to reach its primary completion in 2027-02-28. Interventions recorded: VG2025; AK112. Conditions listed: Colorectal Cancer With Hepatic Metastases. Primary outcome: Number of participants experiencing dose-limiting toxicities (DLTs); Number of participants with adverse events (AEs) and severity; Objective Response Rate (ORR). Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed unresectable colorectal cancer with liver metastases; adenocarcinoma type". Sites: China. No results are recorded here; the registry entry is the source.
Shares Ivonescimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Akeso, Ivonescimab, Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Ivonescimab, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.
Shares Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot), Rectal cancer, Immune checkpoint inhibitors and the tag colorectal-deep-dive.