Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer

Short-Course Radiotherapy With Tumor-Draining Lymph Node Preservation Followed by PD-1 Inhibitors in pMMR/MSS Stage II-III Rectal Cancer is a phase 2, interventional study registered as NCT07394192 by Peking University Cancer Hospital & Institute, with a registry enrolment figure of 44 participants, started 2026-02-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: short-course radiotherapy that preserves tumor-draining lymph nodes. Conditions listed: Rectal Cancer; Radiotherapy; PD-1 Inhibitor. Primary outcome: pathologic complete response rate. Colorectal eligibility wording from the registry: "* Fibrocolonoscopy or digital rectal examination indicates that the distal border of the lesion is located 5-10 cm from the anal verge". No results are recorded here; the registry entry is the source.