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A phase 2 trial in colorectal cancer, run by Ismail Gögenur, not yet recruiting.
Neoadjuvant Immunotherapy and Organ-sparing Treatment in Patients With Stage I-III dMMR Colon Cancer is a phase 2, interventional study registered as NCT07409844 by Ismail Gögenur, with a registry enrolment figure of 152 participants, started 2026-03-01 and due to reach its primary completion in 2028-03-01. Interventions recorded: 1 Cycle of Pembrolizumab; 2 Cycles of Pembrolizumab; 3 Cycles of Pembrolizumab; Additional Cycle of Pembrolizumab. Conditions listed: DMMR Colorectal Cancer; Colon Cancer Stage I; Colon Cancer Stage II/III; Pembrolizumab; Immunotherapy. Primary outcome: Proportion of patients with clinical complete response (cCR). Colorectal eligibility wording from the registry: "Clinical UICC stage I-III dMMR colon carcinoma". Sites: Denmark. No results are recorded here; the registry entry is the source.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.
Shares Mismatch-repair deficient (MSI-high) colorectal cancer, Colon cancer (adenocarcinoma of the colon), Colorectal cancer trials open today (registry snapshot) and the tag colorectal-deep-dive.