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A phase 1 trial of REC-4539 run by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc., now recruiting.
Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors is a phase 1 interventional study registered as NCT07517198 by Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc., with 40 participants planned, started 2026-04-13. Conditions recorded: Solid Tumor, Small Cell Lung Cancer (SCLC), High Grade Neuroendocrine Cancer, Small Cell Carcinomas of Non-lung Origin, Non-small Cell Lung Cancer (NSCLC), Prostate Cancer, Ovarian Cancer, Renal Carcinoma (Clear and Non-clear Cell), Head and Neck Squamous Cell Carcinoma (HNSCC), Hepatic Cancer, Gastric Cancer and Triple-negative Breast Cancer (TNBC). Interventions recorded: EXS74539. OnCo files the registry's Hepatic Cancer under its liver cancer page.
Shares Recursion Pharmaceuticals, Head and neck squamous cell carcinoma, Ovarian cancer, Triple-negative breast cancer (TNBC) and the tag pipeline.
Shares Renal cell carcinoma, Hepatocellular carcinoma, Gastric & gastro-oesophageal junction cancer, Head and neck squamous cell carcinoma and the tag pipeline.
Shares Head and neck squamous cell carcinoma, Ovarian cancer, Triple-negative breast cancer (TNBC), Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Head and neck squamous cell carcinoma, Triple-negative breast cancer (TNBC), Non-small-cell lung cancer and the tag pipeline.
Shares Renal cell carcinoma, Head and neck squamous cell carcinoma, Ovarian cancer, Triple-negative breast cancer (TNBC) and the tag pipeline.
Shares Small-cell lung cancer, Hepatocellular carcinoma, Head and neck squamous cell carcinoma, Non-small-cell lung cancer and the tag pipeline.
Shares Gastric & gastro-oesophageal junction cancer, Head and neck squamous cell carcinoma, Ovarian cancer, Metastatic cancer (cancer that has spread) and the tag pipeline.
Shares Gastric & gastro-oesophageal junction cancer, Head and neck squamous cell carcinoma, Ovarian cancer, Triple-negative breast cancer (TNBC) and the tag pipeline.
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