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A phase 2 trial of fOLFOX (5-FU, leucovorin, oxaliplatin), fluorouracil (5-FU), leucovorin (folinic acid), bevacizumab and other drugs in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.
FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II) is a phase 2, randomised interventional study registered as NCT07621497 by Sun Yat-sen University, with a registry enrolment figure of 229 participants, started 2026-06-01 and due to reach its primary completion in 2029-06-01. Interventions recorded: Oxaliplatin; 5-Fluorouracil; Levofolinic Acid For Injection; Calcium Folinate; Bevacizumab; Cetuximab (EGFR inhibitor). Conditions listed: Metastatic Colorectal Cancer (CRC). Primary outcome: Progression-Free Survival（PFS）. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed unresectable metastatic colorectal cancer with no prior treatment for unresectable or metastatic disease". Sites: China. No results are recorded here; the registry entry is the source.
The full inclusion and exclusion criteria are on the registry record. Read 2026-10-07. Recruiting overall does not mean a particular site is open; ask the study team.
ClinicalTrials.gov data courtesy of the US National Library of Medicine.
Shares Cetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin), Bevacizumab, Platinum agents and the tag colorectal-deep-dive.
Shares Leucovorin (folinic acid), Cetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU) and the tag colorectal-deep-dive.
Shares Cetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin), Bevacizumab, Platinum agents and the tag colorectal-deep-dive.
Shares Cetuximab, Fluorouracil (5-FU), Bevacizumab, Monoclonal antibodies and the tag colorectal-deep-dive.
Shares Leucovorin (folinic acid), FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU), Bevacizumab and the tag colorectal-deep-dive.
Shares Leucovorin (folinic acid), Fluorouracil (5-FU), Bevacizumab, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Leucovorin (folinic acid), Fluorouracil (5-FU), Bevacizumab, Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Cetuximab, Fluorouracil (5-FU), Bevacizumab, Monoclonal antibodies and the tag colorectal-deep-dive.
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