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A phase 1/2 trial of fluorouracil (5-FU), leucovorin (folinic acid), bevacizumab (glioblastoma use), fOLFOX (5-FU, leucovorin, oxaliplatin) and other drugs in colorectal cancer, run by Lepu Biopharma Co., Ltd., not yet recruiting.
A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer is a phase 1/2, interventional study registered as NCT07737600 by Lepu Biopharma Co., Ltd., with a registry enrolment figure of 316 participants, started 2026-08 and due to reach its primary completion in 2028-12. Interventions recorded: MRG007; 5-Fluorouracil / Leucovorin Calcium; Bevacizumab; Oxaliplatin; PD-1/VEGF antibody; Capecitabine. Conditions listed: Advanced Colorectal Cancer. Primary outcome: Dose Limiting Toxicity (DLT); Serious Adverse Events (SAEs); Adverse Event (AE). Colorectal eligibility wording from the registry: "Pathologically confirmed, unresectable locally advanced or metastatic colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Fluorouracil (5-FU), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), Leucovorin (folinic acid), Fluorouracil (5-FU), Colon cancer (adenocarcinoma of the colon) and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Capecitabine, Platinum agents and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Capecitabine, Platinum agents and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Capecitabine, Platinum agents and the tag colorectal-deep-dive.
Shares Bevacizumab (glioblastoma use), FOLFOX (5-FU, leucovorin, oxaliplatin), Capecitabine, Platinum agents and the tag colorectal-deep-dive.
Shares Leucovorin (folinic acid), FOLFOX (5-FU, leucovorin, oxaliplatin), Fluorouracil (5-FU), Capecitabine and the tag colorectal-deep-dive.