Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Rectal Cancer: A Randomized Controlled Trial

Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Rectal Cancer: A Randomized Controlled Trial is a phase 1/2, randomised interventional study registered as NCT07755124 by West China Hospital, with a registry enrolment figure of 140 participants, started 2026-08-14 and due to reach its primary completion in 2028-08. Interventions recorded: Arginine-Deprived Diet; Short-Course Radiotherapy (SCRT); CAPOX + PD-1 Inhibitor. Conditions listed: Rectal Neoplasms. Primary outcome: Complete Response (CR) Rate (pCR + cCR). Colorectal eligibility wording from the registry: "* Locally advanced mid-low rectal cancer staged as cT3, cT4, or node-positive by rectal MRI". No results are recorded here; the registry entry is the source.