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A phase 3 trial of YL201, liposomal irinotecan, fluorouracil (5-FU) and fLOT (5-FU, leucovorin, oxaliplatin, docetaxel) in pancreatic cancer, run by MediLink Therapeutics (Suzhou) Co., Ltd., not yet recruiting.
A Study to Compare the Efficacy and Safety of YL201 With Standard Chemotherapy in Patients With Metastatic Pancreatic Cancer After Failure of Gemcitabine-Based Systemic Chemotherapy is a phase 3, randomised interventional study registered as NCT07803783 by MediLink Therapeutics (Suzhou) Co., Ltd., with a registry enrolment figure of 320 participants, started 2026-10 and due to reach its primary completion in 2029-01. Interventions recorded: Tambotatug pelitecan; Liposomal irinotecan; 5 Fluorouracil; Leucovorin. Conditions listed: Metastatic Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma (PDAC). Primary outcome: PFS by BICR; OS. Pancreatic eligibility wording from the registry: "Participants must have histologically or cytologically confirmed incurable metastatic pancreatic ductal adenocarcinoma (PDAC)". Sites: China. No results are recorded here; the registry entry is the source.
Shares Liposomal irinotecan, FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads) and the tag pancreatic-deep-dive.
Shares Liposomal irinotecan, FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads) and the tag pancreatic-deep-dive.
Shares Liposomal irinotecan, FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads) and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads), Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Liposomal irinotecan, Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads), Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares Fluorouracil (5-FU), Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma, Cytotoxic chemotherapy and the tag pancreatic-deep-dive.
Shares Liposomal irinotecan, Fluorouracil (5-FU), Topoisomerase-I inhibitors (and ADC payloads), Pancreatic cancer trials open today (registry snapshot and UK sites) and the tag pancreatic-deep-dive.
Shares FLOT (5-FU, leucovorin, oxaliplatin, docetaxel), Fluorouracil (5-FU), Pancreatic cancer trials open today (registry snapshot and UK sites), Metastatic pancreatic ductal adenocarcinoma and the tag pancreatic-deep-dive.